The Dalai Lama points out the connection between suffering and afflictive emotions, the “enemy within”. The real enemy is always within, not without. As long as it remains there, lasting happiness cannot be achieved.
Once you have made up your mind to tackle this “enemy within”, to make it count, you realized the true aspiration to seek freedom from suffering.
This is called “renunciation” in Buddhist terms.
Source: Lecture on the Four Noble Truth given in London 1997, organized by the Network of Buddhist Organizations (U.K.) in association with the Office of Tibet (London)